whats the difference between priority mail and priority mail express lies mainly in the delivery speed and cost. Priority Mail is a more affordable option that typically delivers packages in 1–3 business days, depending on the destination. It includes free tracking and $100 insurance for lost or damaged items. On the other hand, Priority Mail Express is a faster, premium service that guarantees overnight delivery to most U.S. locations, including on weekends and holidays. It comes with a higher price tag but offers the fastest possible delivery within the USPS network.